Depressed patients won't get any relief from vitamin D supplementation, a new meta-analysis found.
In a review of seven trials totaling nearly 3,200 patients, the vitamin had no significant effect on depressive symptoms overall, Jonathan Shaffer, PhD, of Columbia University Medical Center, in New York City, and colleagues reported in Psychosomatic Medicine.
However, when looking specifically at patients who had clinically significant depressive symptoms or depressive disorder, the researchers found that there did appear to be a moderately significant effect of vitamin D supplementation on symptoms.
In a press release, the researchers noted that further work should be done on whether vitamin D adds to improvements when patients are also on antidepressants.
They also noted that supplementation may work when depressed patients have an actual deficiency in vitamin D, but more studies are needed.
Have a tip on a vitamin D study? Email Kristina Fiore at k.fiore@medpagetoday.com. You can also catch our vitamin D feed on Twitter, @vitaminDblog.
Other coverage from the Vitamin D Blog:
D's Role in Weight Loss
Iatrogenic Overdose
Inflammatory Markers
Cutting Edema in Athletes' Bones

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